Section 58 of the Constitution provides for the positions of Prime Minister and other Ministers, to be appointed by the Governor-General. The Prime Minister must be a member of the House of Representatives whom the Governor-General believes likely to command the support of the majority of the members of that House.

As the leading Minister of the Government, the Prime Minister presides over Cabinet. He or she leads the Government in the House of Representatives and is the principal spokesperson for Government. The Prime Minister also has residual responsibility for the administration of any department or government property not otherwise specifically provided for.

The Prime Minister chairs Cabinet meetings. Cabinet determines and regulates its own procedures, with support from the Secretary to the Cabinet, but final decisions on procedures rest with the Prime Minister.

Other offices of Minister may be established by Parliament or by the Governor-General, subject to any laws enacted by the Parliament, acting in accordance with the advice of the Prime Minister. Other Ministers must be members of either the House of Representatives or the Senate.

Ministers exercise powers within the Constitution and the law, including:

1. participating in, and supporting, Cabinet decision-making;
2. overseeing and directing the public service in the areas of their portfolio responsibilities;
3. being responsible and accountable to the Parliament; and
4. making delegated legislation if so empowered by statute.

The responsibility of Ministers in the Parliament for government policy as a whole (collective responsibility) and for their own performance in particular (individual responsibility) is a key part of governmental accountability.

Section 58 and other sections of the Constitution also specify the circumstances in which the Governor General may remove the Prime Minister from office and those in which the office of a Minister becomes vacant.

Section 60 of the Constitution provides that the Governor-General, acting in accordance with the advice of the Prime Minister, may assign to any Minister responsibility for any business of the Government, including the administration of any government department. This allocation of responsibilities is set out in the Instrument of Appointment.

The Constitution, in Section 61, also provides for appointment of an acting Prime Minister when the Prime Minister is absent from Grenada or is unable to perform the functions of Prime Minister by reason of illness. In appointing an acting Prime Minister, the Governor-General is required to follow the advice of the Prime Minister, unless it is impracticable to obtain that advice.

The Constitution also includes provisions for appointment of Parliamentary Secretaries from among the Senators and members of the House of Representatives to assist Ministers in the performance of their duties. Parliamentary Secretaries do not attend meetings of the Cabinet.

All Ministers and Parliamentary Secretaries are required to take both the Oath (or Affirmation) of Allegiance and the Oath/Affirmation of Office, as specified in Schedule 3 of the Constitution.